Src Family Kinases Negatively Regulate Platelet-derived Growth Factor α Receptor-dependent Signaling and Disease Progression
نویسندگان
چکیده
منابع مشابه
Platelet-derived growth factor receptor sequences important for binding of src family tyrosine kinases.
We previously demonstrated that src family tyrosine kinases associate with activated platelet-derived growth factor receptors. We have now investigated the requirement for tyrosine phosphorylation sites in the human platelet-derived growth factor receptor for this binding. Tyrosine 857, but not tyrosine 751, is required for efficient association. Furthermore, even though src family tyrosine kin...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2000
ISSN: 0021-9258
DOI: 10.1074/jbc.275.13.9620